Published articles‪


1. K. Yoon, H. W. Kestler, and S. Kim (1998). Growth properties of HSIVnef: HIV-1 containing the nef gene from pathogenic molecular clone SIVmac239. Virus Research 57:27-34


‪2. M. R. Kang, I. S. Lee, J. Chun, S. H. Kim, K. Yoon, K. W. Choi, D-G. Kim, J. M. Kim, W. M. Fitch, Y-O. Shin, and S. Kim (1998). Phylogenetic analysis of the nef gene reveals a distinctive monophyletic clade in Korean HIV-1 cases. Journal of AIDS & Human Retrovirology 17:58-68


‪3. K. Yoon and S. Kim (1999). Lack of negative influence on the cellular transcription factors NF-kB and AP-1 by the nef gene of human immunodeficiency virus type 1. Journal of General Virololgy 80:2951-2956.


‪4. K. Yoon, J. Jeong and S. Kim (2001). Stable expression of human immuno-deficiency virus type 1 Nef confers resistance against Fas-mediated apoptosis. AIDS Research and Human Retroviruses 17:99-104.


‪5. K. Yoon, J. Joeng, H. Yoon, J. Lee and S. Kim (2001). Differential effects of primary human immunodeficiency virus type 1 nef sequences on CD4 and MHC class I. Biochemical and Biophysical Research Communications 284:638-642.


‪6. M. Jin, H. J. Jung, J. J. Choi, H. Jeon, J. H. Oh, B. Kim, S. S. Shin, J. K. Lee, K. Yoon and S. Kim (2003). Activation of selective transcription factors and cytokines by water-soluble extract from Lentinus lepideus. Experimental Biology and Medicine (Maywood), 228:749-758.


‪7. Y. S. Na, K. Yoon, J. G. Nam, B. Choi, J. S. Lee, I. Kato and S. Kim (2004). Nef from a primary isolate of human immunodeficiency virus type 1 lacking the EE(155) region shows decreased ability to down-regulate CD4. Journal of General Virology 85:1451-61.


‪8. K. Yoon, S. Nery, M. L. Rutlin, F. Radtke, G. Fishell and N. Gaiano (2004). Fibroblast growth factor receptor signaling promotes radial glial identity and interacts with Notch1 signaling in telencephalic progenitors. Journal of Neuroscience 24:9497-9506.


‪9. A. W. Duncan, F. M. Rattis, L. N. DiMascio, K. L. Congdon, G. Pazianos, C. Zhao, K. Yoon, J. M. Cook, K. Willert, N. Gaiano and T. Reya (2005). Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance. Nature Immunology 6:314-322.


‪10. K. Yoon and N. Gaiano (2005). Notch signaling in the mammalian central nervous system: insights from mouse mutants. Nature Neuroscience 8:709-715.


‪11. L. Dang, K. Yoon, M. Wang, and N. Gaiano (2006). Notch3 signaling promotes radial glial/progenitor character in the mammalian telencephalon. Developmental Neuroscience 28:58-69.


‪12. M. Hellström, L. K. Phng, J. J. Hofmann, E. Wallgard, L. Coultas, P. Lindblom, J. Alva, A. K. Nilsson, L. Karlsson, N. Gaiano, K. Yoon, J. Rossant, M. L. Iruela-Arispe, M. Kalén, H. Gerhardt, and C. Betsholtz (2007). Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature 445:776-780.


‪13. K. Mizutani*, K. Yoon*, L. Dang, A. Tokunaga, and N. Gaiano (2007). Differential Notch/CBF1 signaling in telencephalic neural stem cells and neuroblasts. Nature 449: 351-355. (*Equally contributed)


‪14. R. Song, Y.-W. Kim, B.-K. Koo, H.-W. Jeong, M.-J. Yoon , K.-J. Yoon, D.-J. Jun, S.-K. Im, J. Shin, M.-P. Kong, K.-T. Kim, K. Yoon, and Y.-Y. Kong (2008). Mind bomb 1 in the lymphopoietic niches is essential for T and marginal zone B cell development. Journal of Experimental Medicine 205:2525-2536.


‪15. Y. Yang, J. Y. Shin, J. M. Oh, C. H. Jung, Y. Hwang, S. Kim, J. S. Kim, K. Yoon, J. Y. Ryu, J. Shin, J. S. Hwang, T. Y. Yoon, Y. K. Shin, and D. H. Kweon (2010). Dissection of SNARE-driven membrane fusion and neuroexocytosis by wedging small hydrophobic molecules into the SNARE zipper. Proceedings of the National Academy of Sciences of the USA 107:22145-22150.


‪16. M. Yang, J. Hong, and K. Yoon (2011) Among gamma-secretase substrates Notch1 alone is sufficient to block neurogenesis but does not confer self-renewal properties to neural stem cells. Biochemical and Biophysical Research Communications 404:133-138.


‪17. J. Jang, J. T. Lee, K. Lee, S. Kim, J. Y. Kim, K. Yoon, and S. Kim (2011). Development of murine leukemia virus-based retroviral vectors with a minimum possibility of cis-activation. Gene Therapy 18:240-249.


‪18. B. Choi, E. Chun, M. Kim, S. T. Kim, K. Yoon, K. Y. Lee, S. J. Kim (2011). Human B cell development and antibody production in humanized NOD/SCID/IL-2Rnull (NSG) mice conditioned by busulfan (2010). Journal of Clinical Immunology 31:253-264.


‪19. K. Koh, J. Kim, Y. J. Jang, K. Yoon, Y. Chae, H. J. Lee, and J. Kim (2011) Transcription factor Nrf2 suppresses LPS-induced hyperactivation of BV-2 microglial cells. Journal of Neuroimmunology 233:160-167.


‪20. B. Choi, E. Chun, M. Kim, S. Y. Kim, S. T. Kim, K. Yoon, K. Y. Lee, and S. J. Kim (2011). Human T cell development in the liver of humanized NOD/SCID/IL-2Rγ(null)(NSG) mice generated by intrahepatic injection of CD34(+) human (h) cord blood (CB) cells. Clinical Immunology 139:321-335.


‪21. S.-R. Jung, N.-J. Song, H. S. Hwang, J. J. An, Y.-J. Cho, H. Y. Kweon, S.-W. Kang, K. G. Lee, K. Yoon, B.-J. Kim, C. W. Nho, S. Y. Choi, K. W. Park (2011). Silk peptides inhibit adipocyte differentiation through modulation of the Notch pathway in C3H10T1/2 cells.Nutrition Research 31:723–730.


‪22. T. Yu, H. M. Ahn, T. Shen, K. Yoon, H. J. Jang, Y. J. Lee, H. M. Yang, J. H. Kim, C. Kim, M. H. Han, S. H. Cha, T. W. Kim, S. Y. Kim, J. Lee, J. Y. Cho (2011). Anti-inflammatory activity of ethanol extract derived from Phaseolus angularis beans. Journal of Ethnopharmacology 137:1197-1206.


‪23. Y. E. Leem, H.-K. Choi, S. Y. Jung, B.-J. Kim, K. Yoon, K. Y. Lee, S. T. Kim (2011) Esco2 promotes neuronal differentiation by repressing Notch signaling. Cell Signaling 23:1876-1884.


‪24. J. Choi, M.-Y. Kim, B. C. Cha, E. S. Yoo, K. Yoon, J. Lee, H. S. Rho, S. Y. Kim, J. Y. Cho (2012). ZYM-201 Sodium succinate ameliorates streptozotocin-induced hyperlipidemic conditions. Planta Medica 78: 12-17.


‪25. J. Jang, K. Yoon, D. W. Hwang, D. S. Lee, S. Kim (2012) A retroviral vector suitable for ultrasound image-guided gene delivery to mouse brain. Gene Therapy, 19:396-403.


‪26. K. Xu, J. Usary, P. C. Kousis, A. P. Aparicio, D.-Y. Wang, W. Wang, A. J. Loch, T. Deng, R. D. Cardiff, K. Yoon, N. Gaiano, V. Ling, J. Beyene, E. Zacksenhaus, T. Gridley, W. L. Leong, C. J. Guidos, C. M. Perou, and S. E. Egan (2012) Lunatic Fringe Deficiency Cooperates with the Met/Caveolin Gene Amplicon to Induce Basal-like Breast Cancer. Cancer Cell, 21:626-641.


‪27. J. Jang, J. Lee, S-T Kim, K.-Y. Lee, S.-T. Kwon, S. Kim, K. Yoon (2012). Polycation-mediated enhancement of retroviral transduction efficiency depends on target cell types and pseudotyped Env proteins: Implication for gene transfer into neural stem cells. Neurochemistry International, 60:846-51.


‪28. J.-Y. Shin, Y. Yang, P. Heo, J.-C. Lee, B. J. Kong, J. Y. Cho, K. Yoon, C.-S. Shin, J.-H. Seo, S.-G. Kim, D.-H. Kweon (2012). pH-responsive high-density lipoprotein-like nanoparticles to release paclitaxel at acidic pH in cancer chemotherapy. International Journal of Nanomedicine 7:2805-2816


‪29. C. H. Jung, J. K. Choi, Y. Yang, H. J. Koh, P. Heo, K. Yoon, S. Kim, W. S. Park, H. J. Shing, D. H. Kweon (2012). A botulinum neurotoxin-like function of Potentilla chinensis extract that inhibits neuronal SNARE complex formation, membrane fusion, neuroexocytosis, and muscle contraction.Pharmaceutical Biology 50: 1157-1167.


‪30. S. M. Yun, S. J. Cho, J. C. Song, S. Y. Song, S. A. Jo, C. Jo, K. Yoon, R. E. Tanzi, E. J. Choi, Y. H. Koh (2013). SUMO1 modulates Aβ generation via BACE1 accumulation. Neurobiology of Aging, 34:650-662.


‪31. J. Jang, J. Ahn, N. Lee, S. T. Kim, D. H. Kweon, J. Y. Cho, K. W. Park, S. Kim, K. Yoon (2013). Ultrasound backscatter microscopy image-guided intraventricular gene delivery at murine embryonic age 9.5 and 10.5 produces distinct transgene expression patterns at the adult stage. Molecular Imaging, 12: 1–6.


‪32. H. H. Choi, H. K. Choi, S. Y. Jung, J. Hyle, B. J. Kim, K. Yoon, E. J. Cho, H. D. Youn, J. M. Lahti, J. Qin, S. T. Kim (2014). CHK2 kinase promotes pre-mRNA splicing via phosphorylating CDK11(p110). Oncogene, 33:108-115.


‪33. J. Ahn, J. Jang, J. Choi, J. Lee, S. H. Oh, J. Lee, K. Yoon, S. Kim (2014). GSK3β, but not GSK3α, inhibits the neuronal differentiation of neural progenitor cells as a downstream target of mammalian target of rapamycin complex1. Stem cells and Development, 23:1121-1133.


‪34. J. Jang, S.-H. Byun, D. Han, J. Lee, J. Kim, N. Lee, I. Kim, S. Park, S. Ha, M. Kwon, J. Ahn,W.-J. Chung, D.-H. Kweon, J. Y. Cho, S. Kim, K. Yoon (2014). Notch intracellular domain deficient in nuclear localization activity retains the ability to enhance neural stem cell character and block neurogenesis in mammalian brain development. Stem cells and Development, 23:2841-2850.


‪35. N. Lee, I. Kim, D. Han, J. Kim, S.-H. Byun, S. Park, S. Ha, M. Kwon, J. Y. Cho, K. Yoon (2015). Creatine inhibits adipogenesis by downregulating insulin-induced activation of the PI3K/Akt signaling pathway. Stem cells and Development, 24:983-994.


‪36. D. Han, S.-H. Byun, J. Kim, I. Kim, S. Park, S. Ha, M. Kwon, K. Yoon (2015). YAP/TAZ enhance mammalian embryonic neural stem cell characteristics in a Tead2-dependent manner. Biochemical and Biophysical Research Communications. 458:110-116.


37. O. Yabut, G. Fernandez, T. Huynh, K. Yoon, SJ. Pleasure (2015). Suppressor of fused is critical for maintenance of neuronal progenitor identity during corticogenesis. Cell reports, 12:2021-2034.


38. O. Yabut, SJ. Pleasure, K. Yoon (2015). A Notch above Sonic hedgehog. Developmental Cell, 33:371-372.


39. O. Yabut, H. X. Ng, G. Fernandez, K. Yoon, J. Kuhn, SJ. Pleasure (2016). Loss of Suppressor of fused in mid-corticogenesis leads to the expansion of intermediate progenitors. Journal of Developmental Biology, 4:29


40. S.-H. Byun, J. Kim, D. Han, M. Kwon, J. Y. Cho, H. X. Ng, SJ. Pleasure, K. Yoon (2017). TRBP maintains mammalian embryonic neural stem cell properties by acting as a novel transcriptional coactivator of the Notch signaling pathway. Development, 144:778-783.


41. J. Kim, D. Han, S.-H. Byun, M. Kwon, S.-J. Cho, Y. H. Koh, K. Yoon (2017). Neprilysin facilitates adipogenesis through potentiation of the phosphatidylinositol 3-kinase (PI3K) signaling pathway. Molecular and Cellular Biochemistry, Feb 27:1-9.


42. T. Ha, K. H. Moon, L. Dai, J. Hatakeyama, K. Yoon, H.-S. Park, Y.-Y. Kong, K. Shimamura, J. W. Kim (2017). The retinal pigment epithelium is a Notch signaling niche in the mouse retina. Cell reports, 19:351-363.


43. D. Han, S.-H. Byun, J. Kim, M. Kwon, S. J. Pleasure, J,-H. Ahn, K. Yoon (2017). Human cytomegalovirus IE2 protein disturbs brain development by the dysregulation of neural stem cell maintenance and the polarization of migrating neurons. Journal of Virology, 91:e00799-17.


44. J. Kim, D. Han, S.-H. Byun, M. Kwon, J. Y. Cho, S. J. Pleasure, K. Yoon (2018). Ttyh1 regulates embryonic neural stem cell properties by enhancing the Notch signaling pathway. EMBO reports, doi: 10.15252/embr.201745472.


[성과 언론보도:] 


45. S.-H. Byun, M. Kwon, S.M. Lee, H. Noh, K. Yoon (2019). PACT increases mammalian embryonic neural stem cell properties by facilitating activation of the notch signaling pathway. Biochemical and Biophysical Research Communications, 28;513(2):392-397.


46. H. J. Lim, J. H. Park, C. Jo, K. Yoon, Y. H.  Koh (2019). Cigarette smoke extracts and cadmium induce COX-2 expression through γ-secretase-mediated p38 MAPK activation in C6 astroglia cells. PLoS One 22;14(2):e0212749.